abstract：:A bile fistula patient was administered intravenously a constant infusion of [3H]mevalonic acid for 4 hrs, and then after 2 weeks he was given a pulse of [3H]mevalonic acid. Bile and blood were collected at frequent intervals. The specific activity-time course curves did not show a precursor-product relationship betwe...

journal_title：Gastroenterology

authors： Schwartz CC,Vlahcevic ZR,Halloran LG,Gregory DH,Meek JB,Swell L

更新日期：1975-12-01 00:00:00

abstract：:Low residue, chemically defined diets containing all essential nutrients in a readily assimilated form, require minimal digestion and are almost entirely absorbed in the upper gastrointestinal tract. Within the past decade, these diets have been reported to provide nutritional support in a variety of clinical situatio...

journal_title：Gastroenterology

authors： Young EA,Heuler N,Russell P,Weser E

更新日期：1975-12-01 00:00:00

abstract：:Chlorpromazine (CPZ) is a long recognized cause of jaundice, but the mechanism by which this agent produces icteric liver disease is not well defined. This study examined some effects of CPZ administration on bilirubin metabolism and biliary secretion in the rat. Acute CPZ treatment (25 mg per kg intravenously) produc...

journal_title：Gastroenterology

authors： Knodell RG

更新日期：1975-10-01 00:00:00

abstract：:It has been suggested that the lower esophageal sphincter (LES) plays an important role in preventing gastroesophageal reflux. This study was designed to determine if abolition of the LES alone is sufficient to induce gastroesophageal reflux and esophagitis. Studies were performed in the Australian brush-tailed possum...

journal_title：Gastroenterology

authors： De Carle DJ

更新日期：1975-09-01 00:00:00

abstract：:The normal surface anatomy of rat hepatocytes, sinusoids, and bile canaliculi was examined by scanning electron microscopy following finger fracture of tissues that were perfused via the portal vein and fixed with 2.5% glutaraldehyde. These normal findings were contrasted with several models of cholestasis, including ...

journal_title：Gastroenterology

authors： Layden TJ,Schwarz,Boyer JL

更新日期：1975-09-01 00:00:00

abstract：:The kinetics of cholesterol and bile acid was determined from a 10-week analysis of the biliary lipids after a single injection of labeled cholesterol in parallel with a conventional 1-week study of primary bile acid kinetics. Six healthy controls and 6 patients with cholesterol cholelithiasis were studied. Two of the...

journal_title：Gastroenterology

authors： Hepner GW,Quarfordt SH

更新日期：1975-08-01 00:00:00

abstract：:In vitro studies have shown that some bile salts inhibit the growth of intestinal bacteria. We investigated the possibility that bile salts might have a similar action in vivo in the ileum by performing serial anaerobic cultures and bile salt analyses on postprandial ileal fluid obtained anaerobically via intestinal t...

journal_title：Gastroenterology

authors： Williams RC,Showalter R,Kern F Jr

更新日期：1975-08-01 00:00:00

abstract：:Adenylate cyclase activity was measured in rat small intestinal villus and crypt cells after in vivo and in vitro exposure to cholera toxin. The increase in intestinal adenylate cyclase induced by cholera toxin in vivo appeared to be largely confined to the villus cell with the largest increase observed for upper vill...

journal_title：Gastroenterology

authors： Weiser MM,Quill H

更新日期：1975-08-01 00:00:00

abstract：:Intravenous administration of nicotine sulfate caused a dose-dependent reduction in the lower exophagel sphincter pressure in anesthetized opossums. The maximal reduction in pressure of 85.0 +/- 2.6% was observed with a dose of 50 mug per kg. The effect of 50 mug per kg was not antagonized by bilateral cervical vagoto...

journal_title：Gastroenterology

authors： Rattan S,Goyal RK

更新日期：1975-07-01 00:00:00

abstract：:Reduction in caloric intake was associated with a greater absolute rise in the serum bilirubin concentration in patients with Gilbert's syndrome and partial hepatic bilirubin uridine diphosphate glucuronyltransferase (UDPG-T) dysfunction compared to patients with hemolytic unconjugated hyperbilirubinemia and normal su...

journal_title：Gastroenterology

authors： Felsher BF,Carpio NM

更新日期：1975-07-01 00:00:00

abstract：:Chloroquine and metronidazole were compared in a randomized trial for the treatment of amoebic liver abscess in 36 patients. An additional 30 patients were treated without randomization. Chloroquine was given according to the standard protocol at Los tangeles County-University of Southern California Medical Center, wh...

journal_title：Gastroenterology

authors： Cohen HG,Reynolds TB

更新日期：1975-07-01 00:00:00

abstract：:The experimental production of gastric ulcers in dogs by subnucosal injection of ulcerogeic agents is described. The most satisfactory agent tested was 95% ethanol, because it produced immediate changes in the mucosa which delineated the size of the ulcer. The depth of ulceration could be controlled and the ulcer heal...

journal_title：Gastroenterology

authors： Otani T,Tatsuka T,Kanamaru K,Okuda S

更新日期：1975-07-01 00:00:00

abstract：:The site and mechanism of alpha-[5-methyl-3-H]tocopherol absorption was investigated using everted rat small bowel sacs incubated in a micellar medium. Mean plus or minus SE absorption rates of the vitamin at 300 muM incubation solution concentration by proximal, medial, and distal small bowel segments were 2.2 plus o...

journal_title：Gastroenterology

authors： Hollander D,Rim E,Muralidhara KS

更新日期：1975-06-01 00:00:00

abstract：:A case of acute bacterial endocarditis is presented in which gallbladder infarction and areas of hepatic infarction were documented. Selective angiography showed findings consistent with emboli to the gallbladder and hepatic circulations. ...

journal_title：Gastroenterology

authors： Henrich WL,Huehnegarth RJ,Rösch J,Melnyk CS

更新日期：1975-06-01 00:00:00

abstract：:In rats fasted 4 days, immunoreactive gastrin concentrations decreased to one-third of the fed levels in antral tissue and to one-eight of the fed levels in serum. The number of antral cells that reacted with fluorescent antigastrin antiserum was also correspondingly decreased. After refeeding, serum gastrin returned ...

journal_title：Gastroenterology

authors： Lichtenberger LM,Lechago J,Johnson LR

更新日期：1975-06-01 00:00:00

abstract：:The effect of magnesium on calcium- and pentagastrin-induced gastric acid secretion and on calcium-induced gastrin secretion were studied in healthy volunteers. Intravenous infusion of calcium gluconate increased serum gastrin concentration as well as gastric volume secretion, acidity, and acid output. Addition of mag...

journal_title：Gastroenterology

authors： Christiansen J,Rehfeld JF,Stadil F

更新日期：1975-05-01 00:00:00

abstract：:By correlating morphological observations with quantitative measurements of net water transport, we determined whether bile salts altered colonic absorptive cells. Epithelial alteration was equivocal and water absorption was uninhibited during infusions of 1 mM deoxycholate or of concentrations of taurocholate less th...

journal_title：Gastroenterology

authors： Saunders DR,Hedges JR,Sillery J,Esther L,Matsumura K,Rubin CE

更新日期：1975-05-01 00:00:00

abstract：:The role of adrenal medullary discharge of catecholamines on inhibition of gastric emptying and small intestinal propulsion after laparotomy was examined in rats. The rate of movement of a 51Cr-labeled liquid test meal, which had been introduced by gastric intubation, out of the stomach and through the small intestine...

journal_title：Gastroenterology

authors： Dubois A,Henry DP,Kopin IJ

更新日期：1975-03-01 00:00:00

abstract：:A patient with ulcerative ileojejunitis was studied by determination of HL-A phenotype, by measurement of jejunal IgA synthesis using a labeled amino acid incorporation technique, and by in vitro organ culture. The patient carried the HL-A8 phenotype in common with 87.5% of patients with gluten-sensitive enteropathy. ...

journal_title：Gastroenterology

authors： Klaeveman HL,Gebhard RL,Sessoms C,Strober W

更新日期：1975-03-01 00:00:00

abstract：:In contrast to the "toxigenic diarrheas" caused by Vibrio cholerae and Escherichia coli, the site and mechanism of fluid loss in shigellosis are unknown. The occurrence of watery diarrhea in shigellosis suggests involvement of the small bowel. Therefore, jejunal, ileal, and colonic water and electrolyte transport was ...

journal_title：Gastroenterology

authors： Rout WR,Formal SB,Giannella RA,Dammin GJ

更新日期：1975-02-01 00:00:00

abstract：:In addition to the previously described molecular forms of gastrin, a new component has been found in high concentrations in the serum of 6 patients with Zollinger-Ellison syndrome. Serum was fractionated by gel filtration, and ion exchange chromatography, and the new component was identified in eluates by radioimmuno...

journal_title：Gastroenterology

authors： Dockray GJ,Walsh JH

更新日期：1975-02-01 00:00:00

abstract：:Fasting hyperbilirubinemia (FHB) has previously been shown to be rapidly reversed by the ingestion of a mixed diet. This study examines the effect of carbohydrate, fat, amino acids, and noncaloric materials on FHB. After an initial fast of 15 to 39 hr, caloric and noncaloric materials were administered by mouth or vei...

journal_title：Gastroenterology

authors： Barrett PV

更新日期：1975-02-01 00:00:00

abstract：:Intraarterial vasopressin has been reported to be effective in the treatment of massive upper gastrointestinal hemorrhage. A prospective, controlled clinical trial comparing conventional treatment with conventional therapy plus intraarterial vasopressin was undertaken. Sixty episodes of upper gastrointestinal hemorrha...

journal_title：Gastroenterology

authors： Conn HO,Ramsby GR,Storer EH,Mutchnick MG,Joshi PH,Phillips MM,Cohen GA,Fields GN,Petroski D

更新日期：1975-02-01 00:00:00

abstract：:Using a radioimmunoassay which detect concentrations of alpha-fetoprotein as low as 5 ng per ml, 38% of 176 patients with viral hepatitis compared with health volunteers and patients with chronic diseases not affecting the liver. When separated into two groups based on histological classification of liver biopsy speci...

journal_title：Gastroenterology

authors： Bloomer JR,Waldmann TA,McIntire R,Klatskin G

更新日期：1975-02-01 00:00:00

abstract：:The interrelationship of the effects of antacids and of rising intragastric pH on serum gastrin levels was examined by comparing the effect of three antacids (Mg(OH)2Al(OH)3, and CaCO3), and their nonbuffering chloride compounds (MgCl2, AlCl3, and CaCl2), on serum gastrin and intragastric pH in duodenal ulcer patients...

journal_title：Gastroenterology

authors： Feurle GE

更新日期：1975-01-01 00:00:00

abstract：:Esophageal ligation in the pylorus-ligated rat significantly inhibited volume, titratable acidity, and titratable acid output and reduced the incidence of ulcers, perforations, and death of 18-hr pylorus-ligated rats. Draining the saliva outside the body of the rat by esophageal cannulation produced a significant incr...

journal_title：Gastroenterology

authors： Brodie DA,Knapp PG

更新日期：1966-06-01 00:00:00